Assessment of Respiratory Function in Conscious Mice by Double-chamber Plethysmography
نویسندگان
چکیده
منابع مشابه
Measuring respiratory function in mice using unrestrained whole-body plethysmography.
Respiratory dysfunction is one of the leading causes of morbidity and mortality in the world and the rates of mortality continue to rise. Quantitative assessment of lung function in rodent models is an important tool in the development of future therapies. Commonly used techniques for assessing respiratory function including invasive plethysmography and forced oscillation. While these technique...
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15 صفحه اولAssessment of respiratory physiology of C57BL/6 mice following bleomycin administration using barometric plethysmography.
BACKGROUND Assessment of deterioration of lung function in animal models of respiratory disease traditionally relies upon quantitating biochemical markers. Plethysmography is a technique for measuring lung function that includes invasive and non-invasive methodologies. OBJECTIVES This study used whole-body barometric plethysmography to characterize change(s) in respiratory physiology of C57BL...
متن کاملEffect of somatic growth, strain, and sex on double-chamber plethysmographic respiratory function values in healthy mice.
Double-chamber plethysmography has been recognized since 1979 as a reference technique to measure pulmonary function values in guinea pigs, but it has not gained attention for use in mice. Theoretically, however, this technique combines the advantages of single-chamber plethysmography with a quantitative assessment of flow and/or volume and a calculated resistance, the interpretation of which i...
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ژورنال
عنوان ژورنال: Journal of Visualized Experiments
سال: 2018
ISSN: 1940-087X
DOI: 10.3791/57778